The following does not directly address the question of VB Automation of NodeXL features.
However, NodeXL does provide support for automation of data collection and analysis.
These posts may offer some guidance on using NodeXL features for automating networks!
A Sample Settings File for NodeXL: An automated recipie for making Twitter network visualizations
http://www.connectedaction.net/2011/06/12/a-sample-settings-file-for-nodexl-an-automated-recipie-for-making-twitter-network-visualizations/
Setting forth: saving NodeXL option settings – how to exchange your expert configurations in NodeXL
http://www.connectedaction.net/2011/04/23/setting-forth-saving-nodexl-option-settings-how-to-exchange-your-expert-configurations-in-nodexl/
Fully automatic: NodeXL can build your network graphs hands free
http://www.connectedaction.net/2010/09/12/fully-automatic-nodexl-can-build-your-network-graphs-hands-free/
How to schedule the creation of a network with NodeXL and Windows Task Scheduler
http://www.connectedaction.net/2010/08/23/how-to-schedule-the-creation-of-a-network-with-nodexl-and-windows-task-scheduler/
Automatic for the people (who use the latest NodeXL!). Release v.1.0.1.128
http://www.connectedaction.net/2010/07/08/automatic-for-the-people-who-use-the-latest-nodexl-release-v-1-0-1-128/
However, NodeXL does provide support for automation of data collection and analysis.
These posts may offer some guidance on using NodeXL features for automating networks!
A Sample Settings File for NodeXL: An automated recipie for making Twitter network visualizations
http://www.connectedaction.net/2011/06/12/a-sample-settings-file-for-nodexl-an-automated-recipie-for-making-twitter-network-visualizations/
Setting forth: saving NodeXL option settings – how to exchange your expert configurations in NodeXL
http://www.connectedaction.net/2011/04/23/setting-forth-saving-nodexl-option-settings-how-to-exchange-your-expert-configurations-in-nodexl/
Fully automatic: NodeXL can build your network graphs hands free
http://www.connectedaction.net/2010/09/12/fully-automatic-nodexl-can-build-your-network-graphs-hands-free/
How to schedule the creation of a network with NodeXL and Windows Task Scheduler
http://www.connectedaction.net/2010/08/23/how-to-schedule-the-creation-of-a-network-with-nodexl-and-windows-task-scheduler/
Automatic for the people (who use the latest NodeXL!). Release v.1.0.1.128
http://www.connectedaction.net/2010/07/08/automatic-for-the-people-who-use-the-latest-nodexl-release-v-1-0-1-128/